It's an unusual side effect, but can happen when your liver and kidneys have trouble metabolizing the medication. hyponatremia, which can also cause other symptoms like headaches, confusion, loss of coordination, and feeling unsteady. This is a sign of low sodium levels, a.k.a. Side effect #5: You feel weak and start slurring your speech. Your doctor may want to weigh the benefits of the drug helping what it was originally intended to help with against how disruptive a particular sexual issue to your life, and they may eventually switch you over to a different prescription.

“We don't really know why this particular side effect comes up, but it’s a longer-term side effect and it’s worse at higher doses.” “A significant portion of people who take the med are affected,” says Hermann. Side effect #4: You're never in the mood.Ī decreased libido, difficulty getting aroused, and difficulty orgasming are all side effects associated with Paxil and SSRIs in general. Typically, you’ll wait one to two weeks, meet with your doc, and then up the dosage, if necessary that gives you time to wait out initial side effects and assess your progress as you get up to an effective dose, says Hermann. “Usually, anxiety is the reason you're taking this med, so I know this might scare people, but it's just a matter of your body getting used to the drug and its longer-term effects,” she says.ĭepression affects about 16 million American adults every year.*Īgain, you can minimize that risk by starting with a low dose and increasing only as tolerated. That sounds counterintuitive, right? But feeling “activated” or a little extra anxious is actually a common feeling when starting Paxil, says Hermann. Side effect #3: You're actually feeling more anxious. And if things don’t settle within one to two weeks, talk to your doctor about potentially switching to a different drug. The best way to minimize this reaction is to start with a low dose and take the meds with food. “So just like the drug can affect arousal in the brain, it can also affect arousal in the gut.” “That’s because there are actually more serotonin receptors in your gut than in your brain,” says Hermann. Gastrointestinal issues are the most common side effects with any SSRI. Side effect #2: You've got stomach issues galore. If you notice an increase in your weight after starting Paxil, talk to your doctor about lifestyle changes, like eating a healthier diet and getting more exercise, or other medication options. Researchers aren't sure why Paxil or other antidepressants can cause weight gain, but they believe it may be linked to its effects on serotonin, which controls and regulates appetite. doi:10.3748/19.1 out of every 6 adults will have depression at some time in their life.* Recent advances in the management of pruritus in chronic liver diseases. 5 reasons you may be at risk for liver disease. Primary biliary cirrhosis and Sjogren’s syndrome: autoimmune epithelitis. Best Practice & Research Clinical Gastroenterology. Coagulopathy in liver disease: a balancing act.

Itch and liver: management in primary care. Hegade VS, Kendrick SF, Rehman J, Jones DE. Sleep disturbances in patients with liver cirrhosis: prevalence, impact, and management challenges. Malnutrition in cirrhosis: more food for thought. Chapman B, Sinclair M, Gow PJ, Testro AG.

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